Let's Experiment: A Guide for Scientists Working at the Bench

How to Design Experiments in Biological Research

Course Overview

Before you step into the lab to do an experiment, you have a long list of questions: How do I design an experiment that will give a clear answer to my question? What model system should I use? What are my controls? What’s an ideal sample size? How can I tell if the experiment worked?

It is overwhelming and easy to feel lost, especially with no guide in sight.

This FREE course tackles the above questions head-on. Scientists from a variety of backgrounds give concrete steps and advice to help you build a framework for how to design experiments in biological research. We use case studies to make the abstract more tangible. In science, there is often no simple right answer. However, with this course, you can develop a general approach to experimental design and understand what you are getting into before you begin.

We will guide you through the steps of planning a well-designed experiment, so by the end of this course, you will have:

  • A detailed plan for your experiment(s) that you can discuss with a mentor.
  • A flowchart for how to prioritize experiments.
  • Tips and best practices for how to get started with an experiment.
  • A lab notebook template that is so impressively organized, it will make your colleagues envious.
  • A framework to do rigorous, reproducible research.

For students and practitioners of experimental biology

We designed this course for graduate students participating in experimental biological research. Advanced undergraduate students may also find this course very helpful, as well as postdocs and staff scientists looking for guidance on these topics.

Includes 5 comprehensive modules and 1 experimental plan

  • Module 1 – AN INTRODUCTION TO EXPERIMENTAL DESIGN: So you have an experiment in mind? This module shows you how to get started.
  • Module 2 – KEY ELEMENTS OF EXPERIMENTAL DESIGN: How to think carefully through key features of an experiment, such as variables, controls, sample size, and replication.
  • Module 3 – ACCOUNT FOR YOUR OWN BIAS: How to identify your own bias as an experimenter and safeguard your experiment from that bias through rigor and transparency.
  • Module 4 – GEAR UP TO DO THE EXPERIMENT: Some tips and best practices on how to familiarize yourself with a protocol, validate key reagents, and keep a good lab notebook.
  • Module 5 – GETTING THE EXPERIMENT TO WORK: Some tips and best practices on how to pilot, troubleshoot, and optimize an experiment.
  • MY EXPERIMENTAL PLAN: As you work through the course, you will be prompted to apply what you’re learning to your own research. Responses to these exercises will be captured in the downloadable document called “My Experimental Plan.” It is organized in a way so that relevant sections may be integrated into your lab notebook.

Built with your schedule in mind

We know you have lots of things to do, so you can take this course as quickly or as slowly as works for you. There are 5 modules in the course and each take about 1.5 to 3 hours of work. There are an average of 7 videos per module; each video is 2 to 6 minutes in length.

This is not a statistics course

We introduce you to some basic statistics concepts that are relevant to the experimental design concepts we teach. However, we don’t dive deeper than that. If you want to learn more, we provide you with some links to outside resources to help get you started.

Without further ado, let’s experiment!

Requirements

There are no requirements necessary to take this class.

How To Do Good Science

Let’s Experiment is the second course in the “How to Do Good Science” series from iBiology Courses. If you haven’t yet, we recommend that you take the first course in this series, called Planning Your Scientific Journey to round out your research training.

  1. Planning Your Scientific Journey teaches you how to ask scientific questions and build a research plan.
  2. Let’s Experiment: A Guide for Scientists Working at the Bench teaches you about experimental design in biological research.
  3. Share Your Research guides you through the steps of creating and delivering a good research talk.

Course Format & Certification

Let’s Experiment is an on-demand, self-paced course. This means that, as soon as you enroll, all course content is available to you and may be consumed at your own pace. For your reference, it took students 6 weeks to complete the whole course in a hosted, synchronized format. They spent on average 1.5-3 hours on the course per week. This includes time spent watching videos, reading text, and doing assessments.

At the end of the course, you can apply to receive a a digital badge and Certificate of Completion to share and keep for your records. Passing requires that you complete all of the required activities for the course, which equals 50% of the total activities.

Take the Course on Canvas

Course Overview

Being successful as a scientist requires more than acquiring knowledge and developing experimental skills. It also requires: (1) asking a good scientific question, (2) establishing a clear plan of action, and (3) seeking advice along the way. These three topics are the focus of this course “Planning Your Scientific Journey,” which is aimed primarily at life science graduate and undergraduate students, but also useful for postdocs, staff scientists, and others who could benefit from learning or reviewing these topics.

By the end of the course, you will have:

  1. Criteria to evaluate a research question.
  2. A plan for how to approach your scientific question and other research goals.
  3. An agenda for a meeting with your mentor to get feedback on your plan.

Planning Your Scientific Journey is an innovative online course.

Engaging videos, along with reflective exercises, offer concrete tools and practical advice to help you navigate the most challenging aspects of developing and planning a research project. Instruction is led by a diverse group of leading scientists, such as Nobel Laureates, accomplished faculty, and junior scientists, who think about different aspects scientific training in deep and meaningful ways.

Whether you have yet to decide on a research question or are well-immersed in a project, this course will help to crystallize your research ideas and goals. So, take charge of your training and enroll in this course now!

If you have any problem starting and using this course, or just want to comment on your experience or offer a suggestion, please email us. And if you’re interested, you can read more about the creation of Planning Your Scientific Journey in this blog post on iBiology.

Requirements

There are no requirements necessary to take this class.

How To Do Good Science

Planning Your Scientific Journey is the first course in the “How to Do Good Science” series from iBiology Courses. Make sure to check out the two other courses in the series to complete your research training!

  1. Planning Your Scientific Journey teaches you how to ask scientific questions and build a research plan.
  2. Let’s Experiment: A Guide for Scientists Working at the Bench teaches you about experimental design in biological research.
  3. Share Your Research guides you through the steps of creating and delivering a good research talk.

Course Format & Certification

Planning Your Scientific Journey is an on-demand, self-paced course. This means that, as soon as you enroll, all course content is available to you and may be consumed at your own pace. For your reference, it took students 6 weeks to complete the whole course in a hosted, synchronized format. They spent on average 2-3.5 hours on the course per week. This includes time spent watching videos, reading text, and doing assessments.

At the end of the course, you can apply to receive a a digital badge and Certificate of Completion to share and keep for your records. Passing requires that you complete all of the required activities for the course, which equals 50% of the total activities.

Take the Course on Canvas

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