Famous Science Discoveries

Learn about revolutionary experiments in biology from the scientists themselves.
Surviving Stress: SOS Response and DNA Repair in Bacteria
Surviving Stress: SOS Response and DNA Repair in Bacteria

Free 9–12 biology & AP Bio lesson on bacterial DNA repair, the SOS response, and antibiotic resistance. Includes modeling, CER activities, and population simulations.

The Tiniest Plankton
The Tiniest Plankton

How Penny Chisholm and her team discovered the invisible yet most abundant photosynthetic organism on the planet

Modeling DNA Replication
Modeling DNA Replication

Engage students with how "the most beautiful experiment" in biology revealed the semiconservative nature of DNA replication with a free video and modeling activity.

Human Nature
Human Nature

The story of CRISPR — the most important scientific discovery of the 21st century.

The Most Beautiful Experiment
The Most Beautiful Experiment

Matt Meselson and Frank Stahl share the story of how they proved semiconservative DNA replication

Good Chemistry
Good Chemistry

Jennifer Doudna & Emmanuelle Charpentier's historic Nobel Prize for CRISPR

Life Recombined
Life Recombined

The Story of Recombinant DNA featuring Janet Mertz and Nobel Laureate Paul Berg

The CRISPR Apostle
The CRISPR Apostle

Rodolphe Barrangou tells the story of his discovery that laid the groundwork for the gene editing revolution

Gregor Mendel’s Famous Genetics Experiment
Gregor Mendel’s Famous Genetics Experiment

Shirley Tilghman tells the story of Mendel’s studies and how his data led to an understanding of how the information within genes is passed from generation to generation.

Tinkering with Nature’s Tools
Tinkering with Nature’s Tools

Feng Zhang shares why CRISPR-Cas9 was such a groundbreaking tool.

Pieces of a Puzzle
Pieces of a Puzzle

Christopher Rudd's seminal experiments on T-Cell Activation

The Discovery of Lung Surfactant
The Discovery of Lung Surfactant

John Clements details his groundbreaking discovery which has saved millions of neonatal lives

The SOS Response in Bacteria
The SOS Response in Bacteria

Evelyn Witkin shares her journey to the discovery of the SOS DNA damage response in bacteria.