Famous Discoveries

Learn about revolutionary experiments in biology from the scientists themselves.
Good Chemistry
Good Chemistry

Jennifer Doudna & Emmanuelle Charpentier's historic Nobel Prize for CRISPR

Charpentier and Doudna transformed science with their groundbreaking research on CRISPR. This film highlights their collaboration, the innovative experiments, and the inspiring process of scientific discovery.
Human Nature
Human Nature

The story of CRISPR — the most important scientific discovery of the 21st century.

The scientific revolution called CRISPR gives humans the power to edit DNA, including our own. The implications are profound and infinite. Scientists are already curing diseases like sickle cell anemia. But how far should we go to change the fundamental nature of who we are as people?
The Most Beautiful Experiment
The Most Beautiful Experiment

Matt Meselson and Frank Stahl share the story of their groundbreaking experiment

Matt Meselson and Frank Stahl share how they devised the groundbreaking experiment that proved semiconservative DNA replication, what it was like to see the results for the first time, and how it felt to be at the forefront of molecular biology research in the 1950s.
The CRISPR Apostle
The CRISPR Apostle

Rodolphe Barrangou tells the story of his discovery that laid the groundwork for the gene editing revolution

The discovery that CRISPR functions as an immune system to protect bacteria against viral infection was made at Danisco, a company looking to improve yogurt production. Rodolphe Barrangou tells the story of his discovery, which laid the groundwork for the gene editing revolution.
Tinkering with Nature’s Tools
Tinkering with Nature’s Tools

Feng Zhang shares why CRISPR-Cas9 was such a groundbreaking tool.

What makes CRISPR-Cas9 such a groundbreaking genome editing tool? Hear from CRISPR-Cas9 pioneer Feng Zhang, Ph.D., who shares not only what makes the tool so unique but also his personal journey into science.
Pieces of a Puzzle
Pieces of a Puzzle

Christopher Rudd's seminal experiments on T-Cell Activation

Researchers are harnessing the power of the human immune system to create new treatments for diseases such as cancer. In this video, meet Christopher Rudd, Ph.D., a scientist whose seminal immunology experiments led to the development of cancer immunotherapies.
Gregor Mendel’s Famous Genetics Experiment
Gregor Mendel’s Famous Genetics Experiment

Shirley Tilghman tells the story of Mendel’s studies and how his data led to an understanding of how the information within genes is passed from generation to generation.

Gregor Mendel’s experiments with pea plants laid the foundation for our understanding of genetic inheritance. In this video, Shirley Tilghman tells the story of Mendel’s studies and how his data led to an understanding of how the information within genes is passed from generation to generation.
The Discovery of Lung Surfactant
The Discovery of Lung Surfactant

John Clements details his groundbreaking discovery which has saved millions of neonatal lives

The expansion of lungs for oxygen exchange is facilitated by lung surfactant. The groundbreaking discovery of this substance was made by Dr. John Clements. In this video, Clements details his scientific journey, touching on his early research, the resistance he encountered in the field, and the discovery of lung surfactant, which has saved millions of neonatal lives.
The SOS Response in Bacteria
The SOS Response in Bacteria

Evelyn Witkin shares her journey to the discovery of the SOS DNA damage response in bacteria.

Evelyn Witkin provides a historical perspective on how working at Cold Spring Harbor (CSH) shaped her scientific career and led to the discovery of the SOS DNA damage response in bacteria.