Homology-directed repair:

How the cell edits DNA after a CRISPR-induced break

Homology-directed repair:

How the cell edits DNA after a CRISPR-induced break

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About the Clip

Sometimes DNA breaks because of insults like x-rays, UV rays, or genetic scissors (e.g., CRISPR-Cas9). DNA breakage can have serious consequences if not corrected. Luckily, the cell has mechanisms to repair those breaks, including one known as homology-directed repair. In this fun animated clip, scientists describe how homology-directed repair works in an accessible way. You’re left with a haiku to better remember it.

This clip was taken from Human Nature, the documentary which explores the discovery and future implications of the CRISPR-Cas9 genome editing technology.

Short Films CRISPR & Genetics

Human Nature, the documentary: www.humannaturefilm.com

CRISPR 101: Homology Directed Repair (Addgene): https://blog.addgene.org/crispr-101-homology-directed-repair

This clip was taken from the feature-length documentary Human Nature. Find credit info at: www.humannaturefilm.com.

Except where otherwise noted, this work is licensed under http://creativecommons.org/licenses/by-nc-nd/4.0/

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